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KMID : 1035620150030030224
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Allergy Asthma & Respiratory Disease
2015 Volume.3 No. 3 p.224 ~ p.227
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Apple-dependent exercise-induced anaphylaxis
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김동현:Kim Dong-Hyun
박경희:Park Kyung-Hee/김영주:Kim Young-Joo/김준호:Kim Jun-Ho/한희재:Han Hee-Jae/박혜정:Park Hye-Jung/박중원:Park Jung-Won/이재현:Lee Jae-Hyun
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Abstract
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Food-dependent exercise-induced anaphylaxis (FDEIA) is a specific variant of anaphylaxis that requires both vigorous physical activity and the ingestion of specific causative foods. In particular, occurrence for FDEIA is rarely associated with apples. A 17-year-old male experienced generalized urticaria, dyspnea, headache, vomiting, and presyncope after ingestion of an apple and then 2 hours of exercise. The skin prick test showed a strong positive reaction to apple crude allergen extract, whereas the results of an open food challenge and exercise provocation tests were negative. However, the exercise test after apple consumption provoked a positive reaction with generalized urticaria, dyspnea, and presyncope. We detected 17 kD IgE-reactive protein band in immunoblotting assay with apple crude extract and patient's serum.
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KEYWORD
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Anaphylaxis, Food hypersensitivity, Immunoblotting
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